ABSTRACT

Substrate specificity is that an enzyme acts on its restricted substrate. However, enzymes show a different degree of specificity. For example, alcohol dehydrogenase catalyzes dehydrogenation of ethanol with high efficiency, but alcohol dehydrogenase catalyzes dehydrogenation of methanol with low efficiency. Such an enzyme is considered to have “low or broad substrate specificity.” Urease only catalyzes the hydrolysis of urea to produce ammonia and carbon dioxide; thus, it is called to have high or narrow substrate specificity.