ABSTRACT
The discovery of ribonucleic acid interference offered new possibilities for functional genome research and for prospective applications of cell transfection with small interfering ribonucleic acid (siRNA) [1]. As a result, the development of transfection assays for investigation of siRNA uptake during cell overgrowth became interesting. In such reverse transcription assay, the siRNA is immobilized in a gel-forming matrix like gelatin or alginate [2]. Arrays of similar gel spots with very
small volumes have to be created on a carrier chip for high-throughput screening (HTS) [3].
