ABSTRACT

Jaundice is a yellow discoloration (p. 271) of the tissues, the body fluids and the glandular secretions due to an excess of bilirubin (p. 36).The yellow coloration of jaundice is not recognisable clinically until the serum bilirubin concentration reaches levels of 50 to 150 µmol/L.These values are greatly in excess of the upper limit of normal, ~20 µmol/L. The circulating bilirubin is either insoluble, unconjugated bilirubin; water-soluble, conjugated bilirubin; or a mixture of both.