ABSTRACT

Trina Huynh,a Andrea C. Backes,b Kelly C. Lee,c Joseph D. Ma,c

Pharmacogenomics is the science of applying genomic information

to determine variability in drug efficacy and toxicity [1]. While

genetic information has been widely used in medicine for single-

gene mutation disorders, this information has been less commonly

used to diagnose and treat complex disorders. Over the last decade,

there has been an explosion of scientific data surrounding the

use of pharmacogenomic information to optimize drug therapy for

complex disorders. Due to the rapid growth in this area, scientists

and clinicians need to be familiar with the most current literature.