ABSTRACT
Utilizing RNAi as a novel therapeutic modality has an enormous
potential to bring the era of personalized medicine from a notion
to reality. However, targeting of RNAi molecules into specific tissues
and cells is still a hurdle. Major attempts are done for developing
carriers that could overcome systemic, local, and cellular barriers.
This chapter will present the recent progress in this emerging field,
focusing on strategies of systemic, active cellular targeting, which is
considered a major challenge for drug delivery.
