ABSTRACT

A renal transplant patient presents with a rise in creatinine shortly after transplantation.

Differential diagnosis

Investigations should be directed at revealing the cause of the graft failure, not excluding associated problems. Like all causes of renal failure, failure of a renal transplant may be classified as prerenal, renal and postrenal. It is reasonable to assume that the patient would have other prominent features of haemorrhage or hypotension; however, all anastomoses created at surgery (ureteric, arterial and venous) are subject to mechanical problems including dehiscence and stenosis. Renal artery pathology could cause prerenal uraemia.