ABSTRACT
Figure 2 VEGF signal transduction. A) Schematic representation of activated and dimerized VEGFR1. Upon ligand binding, docking of adaptor molecules (shown in yellow) to specific phosphor sites occurs, leading to activation of subsequent molecules. The biological outcome of the signaling process is shown inside red oval boxes. B) Schematic representation of activated and dimerized VEGFR1. Upon ligand binding, docking of adaptor molecules (shown in yellow) to specific phosphor sites occurs, leading to activation of subsequent molecules. The biological outcome of the signaling process is shown inside red oval boxes.
