ABSTRACT
What is the systemic inflammatory response syndrome? How does it differ from sepsis? What is the pathological process involved in SIRS? What are its triggers? Name some of the cytokines implicated in the development of SIRS. What is MODS? What are the possible treatments for MODS, SIRS and sepsis? What is activated protein C? Who should receive it? Why is fluid resuscitation alone usually ineffective in cases of severe sepsis?
