ABSTRACT

Prenatal diagnosis has undergone an explosion of growth in

the past decade. The primary impetus for this rapid

expansion has come from the widespread use of prenatal

ultrasonography. Most correctable malformations that can be

diagnosed in utero are best managed by appropriate medical

and surgical therapy after maternal transport and planned

delivery at term. Prenatal diagnosis may influence the timing

(Box 5.1) or the mode (Box 5.2) of delivery, and in some

cases, may lead to elective termination of the pregnancy. In

rare cases, various forms of in utero therapy may be possible

(Table 5.1).