ABSTRACT
Prenatal diagnosis has undergone an explosion of growth in
the past decade. The primary impetus for this rapid
expansion has come from the widespread use of prenatal
ultrasonography. Most correctable malformations that can be
diagnosed in utero are best managed by appropriate medical
and surgical therapy after maternal transport and planned
delivery at term. Prenatal diagnosis may influence the timing
(Box 5.1) or the mode (Box 5.2) of delivery, and in some
cases, may lead to elective termination of the pregnancy. In
rare cases, various forms of in utero therapy may be possible
(Table 5.1).