ABSTRACT

Meconium peritonitis is an aseptic peritonitis caused by spill

of meconium in the abdominal cavity through one or several

intestinal perforations which have taken place during in-

trauterine life. Extravasation of sterile meconium into the

fetal peritoneal cavity causes an intense chemical and foreign

body reaction with characteristic calcification. Often, the

perforations seal before the infant is born. Gastrointestinal

perforations that occur following birth, even though the gut

still contains meconium, constitute an entirely different

group of clinical problems and should not be included in

the syndrome of meconium peritonitis.1,2

Meconium peritonitis was first reported by Morgagni in

1761 in De sedibus et causis morborum. Simpson3 managed to

find 25 cases in 1838 and it was Agerty4 in 1943 who reported

the first successful operation.