ABSTRACT

HDL, LDL, and triglyceride. There is a small but statistically significant increase in the risk of ischaemic stroke, while there is a two-fold increase in the risk of thromboembolic phenomena.

60) d. The contraceptive failure rate is 0.7/100 women-years, a figure that rises to 3.1/100 women-years in those who co-ingest antiepileptics (AEPs). The majority of AEPs are either enzyme inducers or interfere with blood concentration of the pills. Lamotrigine, felbamate and valproic acid are generally safe in women taking oral contraceptive pills. Increasing the oestrogen dose of the pill to at least 50 mg is safer than changing the AEP. Otherwise, using an alternative form of contraception is also advised.