ABSTRACT
Figure 7.9 Simultaneously recorded topography (left, A and B) and recognition (right, A’ and B’) images (TREC images) on J774.A1 cells
obtained with an Fc-functionalized tip. The recognition map of FcγR
domains (black spots) (A’) represents an amplitude reduction due to the
specific binding between Fc molecules on the AFM tip and FcγRs on
the cell surface. During cell surface blocking with free Fc fragments, the
topographical image remain unchanged (B), whereas almost all recognition
spots disappear (B’).
