ABSTRACT
Results of efficiency enhancement studies have been controversial. Increasing the temperature lowers eluent viscosity and system back pressure, leading to the use of (1) higher flow rates (shorter cycle times) [9], (2) longer columns, and (3) smaller particles that enhance efficiency in their own right. However, efficiency is also expected to increase because high column temperatures involve (1) faster adsorption-desorption kinetics, (2) enhanced diffusivity, (3) lower mass transfer resistance (Cm in the van Deemter Equation 6.4), and (4) flatter van Deemter curves.
