ABSTRACT
The potential of ILs as stationary phase modifiers must be investigated, based on the positive effects noted when ILs were added to mobile phases. Surface-confined IL stationary phases are intriguing because effective separations are achieved with aqueous mobile phases almost without organic solvents. Moreover in silica-based long-chain alkylimidazolium stationary phases, the alkyl chain length that does not impact electrostatic interactions may affect the hydrophobicity of the stationary phases. The modification of the reversed phase packing is similar to that obtained under dynamic adsorption of IPRs and the theoretical modelling of the interactions can take advantage of IPC theory.
