ABSTRACT
Since the infancy of modern high performance liquid chromatography (HPLC) in the late 1960s, users have required improved columns to handle more advanced separations. Over the past decade, the enduring development of HPLC has focused on upgrading of column technology and instrumentation to increase the speed and efficiency of separations. Better columns and instrumentation represent the main needs of analytical laboratories to improve data quality and increase sample throughput. Real-time quality control and field analysis are imperative in certain disciplines and these needs helped raise the level of interest in high speed HPLC. Column researchers and manufacturers responded to these needs by enhancing the efficiency and reliability of packing materials.
