ABSTRACT
The hallmarks of Cogan's syndrome (CS) are interstitial keratitis (IK) and vestibuloauditory dysfunction. The history of CS reflects a growing awareness of its potential for causing not only eye and ear disease, but also complex systemic manifestations. In 1945, David G. Cogan, an ophthalmologist at the Harvard Medical School, reported four cases of recurrent nonsyphilitic IK and vestibuloauditory symptoms (1). These cases were similar to a patient who had been described in 1934 with IK and Meniere's disease (2). Cogan was later credited with the first description of this disorder, which now bears his name (1).
