ABSTRACT
The information derived from acute animal toxicology studies is essential for determining the potential toxicity of a chemical to humans and other life forms. The objective of acute studies is to identify the potential toxicology of chemicals, whether commercially available or in development. The underlying premise of using animals in acute testing is that the effects of administration of a synthetic agent on an animal mimic the possible outcomes that the agent may produce in humans or other mammals. The system also implies that short-term tests in animals parallel acute exposure in the human population.
