ABSTRACT
The last several decades have seen significant progress in the development of shortterm tests for the detection of chemical mutagens. This advancement relies on understanding the complex processes leading to the potential carcinogenic actions of these chemicals and how short-term tests screen for human hazards. The
in vitro
tests encompass a wide variety of methods that are quicker, more economical, and more convenient than whole animal tests for the detection of mutations, chromosome breakage, and other genetic effects.
