ABSTRACT

Quantitative Structure-Retention Relationships (QSRRs) are one of the most extensively studied manifestations of Linear Free Energy Relationships (LFERs) (I). It is believed that demonstration of LFERs suggests the presence of a real connection between some correlated quantities, and that the nature of this connection can subsequently be identified. One assumes that correlations among specific quantities are attributable to some physicochemical relationships. The statistically derived correlations encourage attempts to identify the relationships behind them.