ABSTRACT
This chapter provides important tools for solving many of the key problems in bioinformatics including determining the function of a newly discovered genetic sequence; determining the evolutionary relationships among genes, proteins, and entire species; and predicting the structure and function of proteins. It discusses biological problems and proposes new ideas and techniques in the areas of molecular biology and medicine. The chapter studies the effectiveness of different approaches that utilize different data sources, including molecular sequence data and abstracts of research papers. It presents a new approach for gene finding based on a Variable-Order Markov Model and discusses the problem of synonymous codons in the expression of proteins. An application is also presented in the area of concept discovey and classification of scientific abstracts in molecular biology.
