ABSTRACT

This book provides information regarding three major aspects of Aβ metabolism: generation from its precursor, degradation within the brain, and transport out of the brain. It is useful for graduate students, post-doctoral fellows, and scientists both in this and other disciplines.

chapter 2|10 pages

ß-Secretase: Progress and Open Questions

chapter 4|16 pages

γ-Secretase and Presenilin

chapter 5|12 pages

Functional Roles of APP Secretases