ABSTRACT

Surveillance forms a vital part of thyroid cancer management since most of these have indolent disease, but a significant risk of residual/recurrence

Common surveillance tools are serum Tg, anti-Tg Ab, USG of the neck, and RAI scans

RAI scans are commonly used: most patients have an initial RAI scan after total thyroidectomy but they may have a lesser role once an initial post-therapy scan is normal

Risk assessment should be a composite of initial risk estimate and a dynamic real-time estimate based on response to therapy, to guide ongoing management

Surveillance strategies have evolved towards less intensive follow-up for most low-risk patients who have a good response to therapy

More intense surveillance and further imaging (CT/PET-CT) is reserved for patients with advanced disease and greater risk for recurrence

None of the current guidelines are based on high quality evidence, hence surveillance strategies should be adapted to local available expertise, tools, patient profile, and follow-up.