ABSTRACT
Polymeric nanoparticles (PNs) are extensively studied as attractive particulate carriers for drug and cosmetic delivery systems, because of their controlled and sustained-release properties, subcellular size, and biocompatibility with tissue and cells (Grund et al., 2011). For these purposes, PNs are dened as solid colloidal particles ranging in size from 10 to 400 nm. They consist of macromolecular materials, in which the biological active agent is dissolved, entrapped, encapsulated, or absorbed, or to which the active agent is attached (Muthu and Singh, 2009; Dinarvand et al., 2011).
