ABSTRACT
In the last few years, biological research has proven valuable for determining the molecular pathogenesis of many diseases. Molecular biology has been extremely useful in pinpointing the basis of several diseases. Researchers are focusing on the identification of novel methods for the diagnosis of complicated diseases. A new class of genetic tools, using RNAs, has been identified. RNA is involved in virtually all biological processes, so it is not surprising that RNAs or RNA nanotechnology could be associated with diagnosis and detection of disease. RNA molecules possess special functionalities such as aptamers, riboswitches, ribozymes, and small interfering RNAs (siRNAs). These functional modules play novel roles in cell recognition and binding for diagnosis (Zhou et al. 2010), nuclear membrane penetration, brain blood barrier passing (Kumar et al. 2007), and intracellular control and computation via gene silencing and regulation (Benenson 2009).
