ABSTRACT
N.M. Emanuel Institute of Biochemical Physics, Russian Academy of Sciences M.V. Lomonosov Moscow State University, Chemical Department, Chemical Enzymology Division
The enzymatic catalysis as an amazing natural phenomenon of chemical reaction acceleration by protein molecules has attracted much attention in classical chemistry since the very origination of catalysis ideas. The catalysis founder V. Ostwald (1853 - 1932) had distinguished four types of catalysts: contact action of "nuclei", homogeneous catalysis, heterogeneous catalysis, and the action of enzymes. The ideas of enzymatic catalysis origin were most actively developed in the last two decades of the previous century. This is associated with invoking modern physicochemical methods, deep structural investigation of enzymes, application of various molecular-biological and molecular-genetic methods to this field.
