ABSTRACT

Cells need to adopt quickly to changes in their environment.

This often means that they either have to start or to stop the

production of certain proteins within a very short period of time.

Transcriptional regulation involves typically transcription factors,

DNA-binding proteins, that bind to their specific, a few bp long target

site. These proteins are either activators that are needed to switch

on transcription or repressors that switch it off. We will not discuss

here the rather involved transcriptional regulation inside eukaryotic

cells that typically involves a large number of proteins. Instead

we restrict ourselves to the much more simple regulation inside

bacteria. As mentioned in Section 1.2 such cells have no nucleus and

no chromatin. The presence of various repressors is crucial since a

bacterium needs at any given time only a fraction of the proteins that

are encoded in its genome.