ABSTRACT

In this first chapter we introduce the terminology, the main assumptions, and the sta-

tistical models most widely used in adaptive comparative experiments with v treatments. In particular the observed responses are assumed to behave according to one

of the models belonging to the exponential family− see Section 1.3 − and we make the essential assumption that at each step, given the treatment assigned to the exper-

imental unit, the response is independent of the other observations. The role of the

ensuing Fisher information in an adaptive design setting is highlighted in Section 1.4.