ABSTRACT
Several recent reports have shown that end-stage liver disease is the leading cause of death among HIV-infected persons in the highly active antiretroviral therapy (HAART) era. Until a few years ago, HIV infection was an exclusion criteria for organ transplantation. One major concern was that administering iatrogenic immunosuppression to an already im munocompromised individual would lead to an increased risk of opportunistic infections and acceleration of HIV-related disease. However, more recently, because of the significant increase in life expectancy of HIV-infected persons treated with HAART, liver, kidney, kidney-pancreas, heart and lung transplantation have been introduced in this patients population in several centers around the world.
