ABSTRACT

M any bioinformatics methods analyzing data generated from “omics” platforms have been developed for two main objectives: to identify reliable cancer biomarkers for early cancer diagnosis and to discover molecular targets for designed therapeutic intervention. A review o f the bioinformatics literature identifying cancer biomarkers from various platforms is presented in this chapter. The existing problems, solutions and future prospects have been briefly discussed. With the rapid advancement o f bioinformatics techniques and robust “omics” platforms, the biomarker-based applications in clinical oncology will, in the foreseeable future, gradually enter into the mainstream clinics as an important addition to current clinical strategies.