ABSTRACT

DNA glycosylases T4-Pdg (formerly known Removes pyrimidine dimers from DNA 18 1vas as T4 endonuclease V)

Human UDG Removes uracil from DNA 103 4skn E.coli MUG Removes uracil or thymine from DNA

containing G:T or G:U 104 1mwi

Human AAG Removes 3-methylA from DNA 105 1bnk £ coli Aik A Removes 3-methylA from DNA 106 1diz hOGGI Removes 8-oxoG from DNA 107 1ebm B. stearothermophilius Removes oxidized pyrimidine from DNA 108 1p59 Endolll

£. coli MutY Removes adenines from mismatch base pair 109 Irrq Apurinic/apyrimidinic endonucleases

E. coli endonuclease IV Cleaves the DNA backbone at apurinic/ 20 1qum apyrimidinic sites

Human apurinic/ Cleaves the DNA backbone at apurinic/ 110 1dew apyrimidinic apyrimidinic sites endonuclease (HAP1 or APE1)

Other DNA repair proteins 5. cerevisiae Rad4 Binds to the lesion and recruits the 17 2qsh

multi-subunit transcription factor TFIIH £. coli AlkB Oxidizes N-alkylated base lesions to restore

standard bases in single-stranded DNA and RNA

111 3bkz

Human ABH2 Oxidizes 1-methylA damage to restore A in double-stranded DNA

111 3btx

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