ABSTRACT
As we advance with the use ofbetter organs for transplantation and as we identify better means of recovering and preserving organs, we need to characterize the molecular and metabolic landscape of maximally protected organs prior to, during and after transplantation. A fundamental question for the uninitiated would be: What are the most important subjects to address in improving organ recovery and preservation? The answer, as you would imagine, is not simple, due to the complexity associated with organ function and survival. Multiple factors participate in these processes and, therefore, it is difficult to isolate the origin of the mechanisms associated with injury development or protective pathways.
