ABSTRACT

Jorge Lobo's disease is a chronic, deep mycosis. The prognosis for survival is good, although it is reserved with regard to regression of the lesions. The disease is also known as Jorge Lobo's blastomycosis, keloid blastomycosis and Lobo's mycosis. It was first described by Jorge Lobo in 1931 in patients from the Amazon Region. In 1950, Trejos and Romero in Costa Rica described the first case outside Brazil. Other cases were then reported in Colombia, French Guiana, Surinam, Venezuela, Peru, Bolivia and Ecuador. In 1978, Zavala-Velásquez and Pérez reported the first case outside South and Central America, in México (Dermatología Rev Mex 1978; 1:5-12). The Brazilian experience is mainly concentrated in the Northern Region of the country (Manaus and Belem). The fungus has not yet been cultured. Preliminary studies of the viability of Paracoccidioides loboi have been conducted at the Lauro de Sousa Lima Institute (Bauru, Sāo Paulo) in an attempt to obtain a positive culture. Experimental inoculation and therapeutic control of the disease have been undertaken.