ABSTRACT

The classic papers by Dudrick and Wilmore in 1968 describing the first success­ ful method for total parenteral nutrition sparked a resurgence o f interest in clinical nutrition and led to the development o f new techniques and formulas for both parenteral and enteral nutrition.12 There has been intense interest in the role of nutritional therapy in IBD during the 25 years since. Much o f the literature is based on anecdotal, retrospective or uncontrolled data, and spontaneous remissions and exacerbations are characteristic of IBD which makes it difficult to know whether a specific treatment is responsible for observed improvement. However, the large amount of information and the available prospective, randomized, controlled stud­ ies make it possible to draw some general conclusions.