ABSTRACT
Introduction Great gains have been made in our knowledge of hematology based on im-
munophenotypic and genotypic data obtained by special studies such as immunohistochemistry (IH C), flow cytometry (FCM ), fluorescence in situ hybridization (FISH), polymerase chain reaction (PCR) and others. The definitions of many enti ties in the new World Health Organization (W H O ) classification of hematologic neoplasms are based on immunophenotypic and genotypic features, displacing morphology and clinical findings to secondary roles.
