ABSTRACT

Fungal infections of the central nervous system (CNS) occur in both tropical and temperate regions of the world, although these may go more frequently unrecognized in poorer countries where diagnostic facilities are limited. Invasive mycoses most commonly cause meningitis and brain abscess and may affect both immunocompetent as well as immunosuppressed patients. In this chapter, the salient epidemiologic, clinical, radiographic, diagnostic and therapeutic features of CNS fungal infections are reviewed. Table 14.1 lists the important fungi producing CNS infection and the types of clinical disease they typically produce.