ABSTRACT

Molecular imprinted polymers (MIPs) are no longer new materials. Three decades have passed since the early Mosbach and Wulff studies1,2 and the technology is rapidly coming of age. However just what lies ahead for molecular imprinting is far from clear. A search of the literature reveals that researchers have applied molecular imprinting strategies to almost every conceivable problem requiring a molecular recognition solution. From sensors to SPE (solid phase extraction), from column chromatography to catalysis, MIPs have been applied with varying degrees of success.3'8 One area of clear value, and one with a set of uniquely challenging and applicable problems, is drug discovery9 and in particular the process of primary drug screening.