ABSTRACT
Introduction Testicular cancers are relatively rare, but are the most common solid tumor in
males aged 15-35. They have become the most curable of all urologie cancers due to effective diagnostic techniques, sensitive tumor markers, effective multidrug che motherapy, and modifications of surgical technique. More than 95% of testicular tumors are derived from germinal tissue, the remainder originating from nongerminal or stromal cells. The testicular germ cell tumors are classified as seminomatous or non-seminomatous. Seminomas are extremely sensitive to radiation therapy, whereas non-seminomatous germ cell tumors are responsive to platinum-based chemotherapy. The serum tumor markers human beta-subunit chorionic gonadotropin (B-hCG) and alpha-fetoprotein (AFP) are extremely useful in both diagnosing disease and monitoring response to therapy.
