Asymmetric Cell Divisions and Nuclear Migrations of Neural Progenitors: Two Mechanisms that Infl uence Neurogenesis

During the cell cycle, neural progenitors must constantly integrate intrinsic as well as extrinsic signals that infl uence progenitor cell behavior and fate decisions. Asymmetric cell division, in mitosis, and interkinetic nuclear migration, during interphase, are two potential regulators of cell fates decisions during the life-time of a cell. In this chapter, these two features will be introduced and discussed.