ABSTRACT
Mucus lining epithelial surfaces throughout the body poses a critical
barrier to the transport of nanoparticle (NP) drug and gene carriers.
Quantitative studies of the barrier properties of physiological mucus
secretions are important in the development of new strategies for
targeting the mucosal epithelium. This chapter summarizes the
physiochemical properties of the mucus barrier, techniques used to
characterize particle transport in mucus, and recent advancements
in this field.