chapter  10
20 Pages

Pathogenesis of Tuberculosis

Host immune responses determine to a large extent the ultimate outcome of infection with Mycobacterium tuberculosis in at least two disparate ways: by participating in the resistance to the pathogen and by contributing to the development of disease. Thus, a better understanding of the cellular and molecular components of the immune system that mediate and regulate these beneficial and deleterious phenomena should lead to improved and novel approaches to the diagnosis, prevention, and control of human tuberculosis.