ABSTRACT

Eosinophilic esophagitis (EoE) is rapidly emerging as a distinctive disorder in pediatric and adult gastroenterology. EoE is a chronic inammatory esophageal disease, characterized clinicopathologically by (1) esophagus-related symptoms and (2) a dense esophageal eosinophilia, both of which persist despite prolonged treatment with proton pump inhibitors. Of note, EoE is neither dened by one single marker, e.g., number of eosinophils in the esophagus, nor by endoscopic ndings.