ABSTRACT

Microfluidic-based particle counting sensors have great advantages over conventional devices and allow the development of accurate, cheap, and portable particle counting devices. The particle counting sensor is an important and widely used device in various areas from environmental to biological applications. The microfluidic resistive pulse technique applies the basic working principle of the Coulter counter to microchannels for counting micro- and submicron particles. The capacitance particle sensor uses a similar principle as that of the Coulter counter. It measures the Alternating current capacitance instead of the Direct current resistance when a micron or submicron particle passes a sensing gate. Similar to a microfluidic Resistive pulse sensor, the capacitance particle sensor has advantages in terms of simple sample preparation, cost, size, and robustness. The light-scattering particle sensor uses the reflected light of the particle. Micro-particle image velocimetry technique can perform particle counting and analysis of the flow field simultaneously.