ABSTRACT

The advent of microuidics over the last 15 years has opened up a new frontier in uid mechanics. The fabrication of small-scale uid devices and the availability of microscopy techniques to probe uid ows has led to the discovery of new and interesting physical phenomena. The concept of a lab-on-a-chip has spawned an industry that strives to miniaturize and popularize the ability to detect, to process, and to analyze biological and chemical specimens on small, inexpensive microuidics-based platforms. However, many of the processes need to be quantitatively characterized with accurate diagnostic techniques. As the device dimension shrinks, bulk properties of the uid medium have become less important, and understanding interfacial and near-wall uid-solid interactions is more vital to the advancement of these technologies. The terms microŽuidics and nanoŽuidics have generally been used

CONTENTS

10.1 Introduction ........................................................................................................................283 10.2 Single-Particle Hydrodynamics .......................................................................................284