ABSTRACT
Multiple emulsions were rst described in 1925 by Seifriz (1925); in 1965, Herbert described these systems in detail as avaccine delivery system (Herbert 1965); and in 1968, Engel investigated the intestinal absorption of insulin in water-in-oil-in-water (W/O/W) multiple emulsions (Engel et al. 1968). In the last 10-20 years, besides different research groups, detailed investigations on these systems were performed by many researchers.
