ABSTRACT
Microencapsulation by solvent evaporation is widely applied in pharmaceutical investigations in order to control drug release. Forming polymer nano-or microspheres can degrade and release the encapsulated drug slowly with aspecic release prole. The sustained drug release has clinical benets: reducing the dosing frequency, more convenience and acceptance for patients, and drug targeting to specic locations resulting in ahigher efciency. The appropriate choice of the encapsulation method to achieve an efcient drug incorporation depends on the hydrophilicity or the hydrophobicity of the drug.
