ABSTRACT

Infectious viral diseases have existed throughout history and

continue to be global threats to public health worldwide. In contrast

to continually evolving vaccines to prevent viral infection, few direct

antiviral therapies have been developed for treatment. The only

drugs inhibiting viruses directly are interferon [1] and nucleoside

analogs [2]. For patients with viral diseases, drugs against bacteria

and parasites will be applied to alleviate the syndromes, while

the viruses are actually wiped out by the immune system. That’s

the reason viruses targeting the immune system, such as human

immunodeficiency virus (HIV), are so difficult to kill. It seems that

prevention is more effective and important than treatment for viral

diseases. Unfortunately, long-term vaccines are unavailable for most

kinds of viruses due to the high mutation rate of viruses [3, 4].