ABSTRACT
Ulcer refers to a discontinuity of the skin exhibiting complete loss of the epidermis that is not short lived. The duration of the ulcer could last from a few weeks to even a few years. Patients suffering from such chronic skin ulcers face a huge loss of quality of life. The patients not only have to endure pain, but also time-consuming outpatient treatment and costs. Leg ulcers are very common, and based on the statistics, 3.5% of all adults in the United States suffer from venous leg ulcers [1]. Chronic ulcerative skin lesions affect about 1.5% of the European population and represent an important medical and social problem [2].
