ABSTRACT

More than standard bone densitometry1, noninvasive and/or non-destructive techniques are capable of providing macro-or microstructural information about bone2. While bone densitometry provides important information about osteoporotic fracture risk, numerous studies indicate that bone strength is only partially explained by bone mineral density (BMD). Quantitative assessment of macrostructural characteristics such as geometry, and microstructural features such as relative trabecular volume, trabecular spacing and connectivity, may improve our ability to estimate bone strength.