ABSTRACT

In the previous chapter we discussed the scientific basis of the two current popular methods, maximum slope and deconvolution, for calculation of perfusion parameters from a computed tomography (CT) perfusion study. This chapter discusses the various necessary data-processing steps and techniques required to produce accurate and reproducible CT perfusion measurements using deconvolution analysis. The data processing required to implement the deconvolution-based method is more involved than for the maximum slope method, and there several interesting issues that can be confusing.