ABSTRACT
Squamous cell carcinoma and adenosquamous carcinomas that originate in the prostate are rare. The largest series is of 33 cases.12 In this series, men with an average age of 68 years presented with bladder outlet obstruction and dysuria. The incidence is less than 1% of all prostate carcinomas.13-16 Many cases of prostatic carcinoma with squamous differentiation are detected after radiation or hormonal therapy for prostatic adenocarcinoma. The time course for the appearance of squamous differentiation in the carcinoma varies from 3 months17 to many years (up to 9) after therapy.18
Squamous metaplasia and HPV infection do not appear to predispose to this development.14 Prostatic squamous cell carcinoma has been shown to occur in association with prostatic schistosomiasis.19
